Hasbrouck Heights firefighters were called to the two-vehicle crash at Williams Avenue in the southbound lanes around 6 p.m., they said.
Photos from the scene show the crash involved a Jeep Grand Cherokee and some other type of SUV.
Crews stabilized the vehicle and extricated the patient, firefighters said in a release.
"Speedy dry was applied to the fluid spill and the unconscious driver was evaluated by EMS," the fire department said.
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